Steroid abuse can also affect the heart (cardiovascular system) and cholesterol (lipid profile). Generally, in studies where steroids are abused, HDL-cholesterol (the good stuff) declines, and LDL-cholesterol tends to go up. Yeah, the good cholesterol goes down and the bad cholesterol goes up. In a related area, the heart often has to work harder because of this, and there also seems to be a steroid-related mild hypertrophy of the left ventricle which is accompanied by a decreased diastolic relaxation. This is very unclear, as regards steroid use, with regards to potential for reversibility and what portion is due to steroid use and what portion is due to training, which also increases ventricle size. Also in a related vein (ha ha) are increases in diastolic blood pressure. All of this increases risk for cardiovascular disease.
Edward Norton claims that he worked out for three months and ate lots of protein to add the 30 pounds of muscle for the role. We don’t buy it. Apparently Arnold Schwarzenegger, a close friend of Mr. Norton’s was concerned and had contacted him to ask if he was using anabolic steroids in his preparation for the the film. American History X ‘s main character Derek Vineyard needed to be a jacked and menacing figure in order to be a terrifying nazi. And, let’s be honest, if white supremacists all looked like the “before” picture up there, it’d be hard to take racism seriously.