A study conducted by Chambers et al. in 2006 indicated that newborns whose mothers had started taking an SSRI such as Paxil after twenty weeks of becoming pregnant are six times more likely to develop PPHN than the general population. Another study by Källén et al. reported a significant relationship between the occurrence of PPHN and the use of antidepressant drugs such as Paxil during the first trimester of pregnancy. No association between the use of the SSRI drug during the third trimester of pregnancy and PPHN was found by the study conducted by Andrade et al. The FDA updated its safety warning in December 2011. As the review of more recent studies yielded additional findings that had to be taken into account, it was concluded that a final decision cannot yet be established about the relationship between the use of SSRIs and the development of PPHN.
I used creatine 8 or so years ago, had great gains, ( it was the exact same product then & dont tell me its gotten better becasue its effervescent or some .) But I also had a frequent & uncomfortable need to urinate that was NOT just from consuming extra liquid, but from my kidneys being put on overload & doing damage to them with this stuff. I drank plenty of water, took a little less than the recommended dose & was having the urination problem for years after the use of creatine… I also was very short tempered with my family & young kids at the time I took it as it altered my mood.
I also have a friend who underwent a kidney transplant, that if he didnt get, he would have died . the reason for his kidney failure was creatine & he would tell you to stay far away from it as it almost costed him his life. This stuff is absolutely no good-
Adverse reactions reported since market introduction that were temporally related to CYMBALTA therapy and not mentioned elsewhere in labeling include: acute pancreatitis , anaphylactic reaction, aggression and anger (particularly early in treatment or after treatment discontinuation), angioneurotic edema, angle-closure glaucoma , colitis ( microscopic or unspecified), cutaneous vasculitis (sometimes associated with systemic involvement), extrapyramidal disorder, galactorrhea , gynecological bleeding, hallucinations, hyperglycemia , hyperprolactinemia, hypersensitivity, hypertensive crisis, muscle spasm, rash, restless legs syndrome, seizures upon treatment discontinuation, supraventricular arrhythmia , tinnitus (upon treatment discontinuation), trismus , and urticaria .