We have further found that 2-methoxyoestradiol inhibits DNA synthesis and cell division in airway smooth muscle stimulated with a range of growth factors, including FCS and bFGF. In addition, serotonin-stimulated increases in protein synthesis rates are inhibited by 2-methoxyoestradiol, raising the possibility of anti-hypertrophic effects, in addition to inhibition of cell proliferation. Our observations, together with the anti-angiogenic activity of 2-methoxyoestradiol, indicate that this and related compounds may have therapeutic value in the treatment of airway diseases characterised by inflammation as described above, in particular in the treatment of chronic asthma, with particular impact on the airway wall remodelling and hence on airway hyperresponsiveness. Analogues of 2-methoxyoestradiol were also tested for their ability to inhibit DNA synthesis, and the results indicate that these also may have therapeutic value.
For the low testosterone patient, he will have the easiest time combating the side effects of Sustanon 250. In this case, while side effects are possible he is merely replacing the testosterone he’s lacking. Then we have the performance athlete and he will be taking his testosterone levels far above and beyond what could ever be naturally produced. Most men can tolerate high testosterone levels very well but there is generally a cutoff point. However, this cutoff point can vary greatly from one man to the next. Further, this individual will need to exercise more caution than the low testosterone patient and often take steps that a therapeutic setting may not require. In order to help you understand the possible side effects of Sustanon 250 we have broken them down into their separate categories along with all the information you’ll need.